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Believe that the main thing is that there is no resistance to it, only that of humans”, comments Silvia about the advantages of the treatment, highlighting that the patient's prejudice against the fly is the true resistance. This is because the larva is immune to the biofilm of many drug-resistant bacteria, and as it devours the necrotic tissue, it eats the bacteria present along with it. The antibiotic, on the other hand, often does not act on this same biofilm, as it cannot penetrate and kill the bacteria. Which leads to the next advantage: recovery time. The veterinarian reports that, in the conventional treatment of a serious injury, the region is completely cleaned in at least one month. In biotherapy, in turn, in four applications (each lasting 48 hours), totaling one week, total cleansing is achieved. “So much so that we have had cases of horses with injuries for years, that, with an application of biotherapy, the bacteria were removed and the animal recovered”, she recalls. Regarding the action of the larva inside the wound, the researcher emphasizes that it is more precise, because it only removes the dead tissue.
As healthy tissue is spared, there is no need for reconstruction procedures. These, in traditional treatments for deep injuries, end up being required because the contamination is deep within the injury. “As sometimes happens on the leg, when the wound on the outside is small, but inside it is a pocket of contamination”, reveals Silvia, who continues: “for the professional to have access to this, they would have to open and clean the wound, having there is a loss of healthy tissue. It’s a bigger scar.” The opposite of the larva, as, when placed in the external hole, it goes deeper and devours the necrotic DM Databases part. Due to its size, it can access small spaces. This cleans without having to open the wound. When it's time to leave, she heads towards the surface. By avoiding more surgeries to clean and restore tissue, excessive blood loss is also avoided in biotherapy. “Conventional cleaning is done with a scalpel. So, no matter how skilled the professionals are, they end up removing the good, healthy tissue as well,” says Silvia. The veterinarian also shares that people's discomfort with the practice comes largely from the.

Photo of a horse, from the front, in a stall, with part of its head bandaged Success story: after surgery to remove a tumor from the face that had become infected, larvae were used to control the infection. The treatment was carried out by veterinarian Gabriele Biavaschi (Photo: personal archive) “The action of the larva is mechanical, that is, when we place it on an injury, it mechanically eats the necrotic tissue and eliminates substances. She sees that rotten and stinking meat as if it were a banquet, and salivates”, he reiterates. When it starts to salivate, it produces proteolytic enzymes, which will break down the bad tissue for the larva to absorb, since it has no teeth and cannot chew. Furthermore, larval movement itself stimulates new tissue to come, granulation tissue. No less important, the professor recalls that edema – swelling in the tissues due to excess retained fluid – is reduced by therapy. Due to the simplicity of the process, one can guess the next positive point of the treatment: there is no need for anesthesia, as the action of the larva hardly causes pain. Relevant factor for patients who suffer from pressure sores, when the skin suffers from prolonged pressure and lack of blood supply.
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